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(4*35 <; + 2*18 <;); 105-000816-00 C6=0 D>AD0B070 (4*35<; +2*18 <;); 105-000822-00 ;L1C<V= (4*40 <;); 105-000823-00 V;>: 7030;L=89 (4*40 <;); 105-000850-00 V;V@C1V= 7030;L=89 (4*20<; + 1*20 <;); 105-000827-00 V;V@C1V= ?@O<89 (VOX) (4*35 <; + 2*18 <;); 105-000847-00 ;LD0-<V;070 (1*38 <; + 1*10 <;); 105-000824-00 !5G>28=0 (4*35 <; + 2*18 <;); 105-004614-00 @50B8=V= (2*27 <; + 1*18 <;); 105-000820-00 %>;5AB5@8= 7030;L=89 (4*40 <;); 105-000821-00 "@83;VF5@848 (4*40 <;); 105-004615-00 @50B8=:V=070 (235 <; + 118 <;); 0;V7> (C 8 Q) (240 <;+116 <;+0;V1@0B>@11.5 <;+>=B@>;L 15 <;); 105-000849-00 ;N:>70 (GOD-POP <5B>4) (4*40 <; + 2*20 <;); 105-000748-00 G8ICNG89 @>7G8= (CD80), 1; U-11 "5AB>2V A<C6:8 4;O A5G>28E 0=0;V70B>@V2; 0:B0B453V4@>35=070  (435 <; + 218 <;); 105-000848-00 !5G>20 :8A;>B0 (4*40 <; + 2*20 <;); 105-000836-00 LDL-E>;5AB5@8= (140<; + 114 <;); 0<03;CB0<V=B@0=AD5@070 " (435<;+218<;); 105-001127-00 C;LB8:0;V1@0B>@ 1D *3<;; 105-009117-00 >=B@>;L ClinChem (@V25=L1) (105<;); 105-001128-00 0;V1@0B>@ V?V48 (51 <;); ;N:>70 !?- =01V@ @5035=BV2 4;O 287=0G5==O :V;L:>ABV 3;N:>78 2 A8@>20BFV/?;07<V :@>2V, 500 287=0G5=L; ;0=V=0<V=>B@0=AD5@070-:V=.!? 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01> <VABOBL BV;L:8 >=>:;>=0;L=V 0=B8BV;0.; V>DV;V70B; 57 >7=0: 7@>AB0==O 10:B5@V9 01> 3@81V2, >A04C V V=H8E AB>@>==VE 4><VH>:; !B01V;L=VABL: -ACE89 @5035=B ?VA;O @>72545==O - =5 <5=H5 18 <VAOFV2, #?0:>2:0 - ?> 1 D;\1 <;, ?V?5B:0 2 :><?;5:BV; 2442737 5035=B 4;O <V:@>1V>;>3VG=>3> B5ABC =0 ?@>4C:FVN :>03C;078, IVD (4V03=>AB8:0 in vitro );07<0 :@>;OG0 F8B@0B=0 ACE0, 10 0<?C; ?> 1 <;1=01V@/2;OT A>1>N ;V>DV;V7>20=C ?;07<C :@>;OGC F8B@0B=C >B@8<0=C 7 :@>2V :@>;8:V2 H;OE>< 7<VHC20==O 7 10% @>7G8=>< =0B@VN ;8<>==>:8A;>3>. $>@<0 28?CA:C 2 0<?C;0E.2537435 8A: IVD (4V03=>AB8:0 in vitro ) 4;O 28?@>1C20==O =0 A?@89=OB;82VABL 4> 078B@><VF8=C8A:8 SD204 Azithromycin / 78B@><VF8= 15 <:36D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << 7 =04@C:>20=8< AZM 15 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V22645445 <V:0F8=>2V 48A:8 4;O B5ABC20==O =0 GCB;82VABL, IVD (4V03=>AB8:0 in vitro )8A:8 SD035 Amikacin/<V:0F8= 30 <:3.3 D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< AK 10 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V22746191 <?VF8;V=>2V 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD002 Ampicillin/<?VF8;V= 10 <:3.3D;0:>=8A:8 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< AMP 10 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V22859213 0=:><VF8=, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD045 Vancomycin/0=:><VF8= 30 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< VA 30 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V22945529 5=B0<VF8=>2V 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD016 Gentamicin / 5=B0<VF8= 10 <:3.4D;0:>=8A:8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< GEN 10 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V23038575 >:A8F8:;V= 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD012 Doxycycline Hydrochloride / >:A8F8:;V= 30 <:3.3D;0:>=8A:8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< DO 30 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V23141910 8A: IVD (4V03=>AB8:0 in vitro ) 48A:@5B870FVW A?@89=OB;82>ABV 4> 5@8B@><VF8=C8A:8 SD013 Erythromycin 15 mcg / @8B@><VF8= 15 <:3.3D;0:>=8A:8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< E 15 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V23261975 B@0:>=07>;, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD276 Itraconazole / B@0:>=07>; 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10 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> ?@>B83@81:>28E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< CC 10 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V23659199 !C;LD0<5B>:A07>;/ B@8<5B>?@8<, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD010 Co-Trimoxazole25 mcg (Trimethoprim/Sulphamethoxazole) (1.25/23.75 mcg) / >-B@8<>:A07>; 25 <:3 ("@8<5B>?@8</!C;LD0<5B>:A07>; 25 <:3 1.25/23).3D;0:>=8A:8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< !OT 25 (1.25/23.75 mcg) C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V23761977 V:>=07>;, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD272 Miconazole/V:>=07>; 50 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> ?@>B83@81:>28E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< MIC 50 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V23859164 VAB0B8=, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD025 Nystatin NS 100 Units/VAB0B8= 100 >48=8FL.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> ?@>B83@81:>28E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< NS 100 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V23959159 VB@>DC@0=B>W=, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD023 Nitrofurantoin / VB@>DC@0=B>W= 300 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< NIT 300 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V24059162 >@D;>:A0F8=, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD057 Norfloxacin/>@D;>:A0F8= 10 <:3.4D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< NX 10 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V24159168 :A0F8;V=, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD088 Oxacillin/:A0F8;V= 1 <:3.3 D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< OX 1 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V2429173 5=VF8;V=/=>2>1V>F8=, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD028 Penicillin-G P 10 / 5=VF8;V= (5=78;?5=VF8;V=) 10 >48=8FL.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< P 10 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V24359183 8D0<?VF8=, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD030 Rifampicin / VD0<?VF8= 5 <:3. 100 48A:V2 C D;0:>=V.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< RIF 5 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V24459193 !B@5?B><VF8=, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD031 Streptomycin / !B@5?B><VF8= 10 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< S 10 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V24559209 ">1@0<VF8=, 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD154 Tobramycin (">1@0<VF8=)4D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 <<. $0AC20==O 100 48A:V24642830 8A:8 4;O B5ABC20==O =0 GCB;82VABL 7 D;C:>=07>;><, IVD (4V03=>AB8:0 in vitro )8A:8 SD114 Fluconazole/$;N:>=07>; 10 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> ?@>B83@81:>28E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< FLC 10 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V24738567 8A: IVD (4V03=>AB8:0 in vitro ) 4;O 4V03=>AB8:8 GCB;82>ABV 4> E;>@0<D5=V:>;C8A:8 SD006 Chloramphenicol / %;>@0<D5=V:>; 30 <:3.3D;0:>=8A:8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 284: 1C<06=V 48A:8 4V0<5B@>< 6 << 7 =04@C:>20=8< ! 30 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V24840755 8A: IVD (4V03=>AB8:0 in vitro ) 4;O 4V03=>AB8:8 GCB;82>ABV 4> F5D07>;V=C8A:8 SD047 Cefazolin/&5D07>;V= 30 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: ?0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< CZ 30 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V24937573 &5D5?V< <V=V<0;L=0 V=3V1C20;L=0 :>=F5=B@0FVO IVD (4V03=>AB8:0 in vitro )8A:8 SD219 Cefepime / &5D5?V< 30 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< CPM 30 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V25038657 &5D>?5@07>=/AC;L10:B0< <V=V<0;L=0 V=3V1C20;L=0 :>=F5=B@0FVO IVD (4V03=>AB8:0 in vitro )8A:8 SD203 Cefoperazone/Sulbactam / &5D>?5@07>=/!C;L10:B0< 75/30 <:3 (!C;L?5@07>=). 3 D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< CFS 75/30 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V25146005 &5D>B0:A8<>2V 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD040 Cephotaxime / &5D>B0:A8< 30 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< !TX 30 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V25237441 8A: IVD (4V03=>AB8:0 in vitro ) 4;O 28?@>1C20==O =0 A?@89=OB;82VABL 4> F5DB07848<C8A:8 SD062 Ceftazidime / &5DB07848< 30 <:3.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< CAZ 30 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V25344483 8A:8 4;O B5ABC20==O =0 GCB;82VABL 7 F5DB@V0:A>=><, IVD (4V03=>AB8:0 in vitro )8A:8 SD065 Ceftriaxone / &5DB@V0:A>= 30 <:3. 100 48A:V2 C D;0:>=V.4D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< CTR 30 2 F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V25442487 8A:8 4;O B5ABC20==O =0 GCB;82VABL 7 F5DC@>:A8<>< =0B@VN, IVD (4V03=>AB8:0 in vitro )8A:8 SD061 Cefuroxime / &5DC@>:A8< 30 <:3. 100 48A:V2 C D;0:>=V.3D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< CXM 30 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V25545359 &8?@>D;>:A0F8=>2V 48A:8 4;O B5ABC20==O =0 GCB;82VABL IVD (4V03=>AB8:0 in vitro )8A:8 SD060 Ciprofloxacin / &8?@>D;>:A0F8= 5 <:3.4D;0:>=8A:8 7 0=B81V>B8:0<8 4;O 287=0G5==O GCB;82>ABV <V:@>>@30=V7<V2 4> 0=B8<V:@>1=8E ?@5?0@0BV2. >2=VH=V9 283;O4: 0?5@>2V 48A:8 4V0<5B@>< 6 << V7 =04@C:>20=8< CIP 5 C F5=B@V :>6=>W AB>@>=8 48A:0. $0AC20==O 100 48A:V25662451 Escheric hia coli, G8A;5== V HB0<8, 0=B835= 8 V7>;OBC :C;LBC@ 8 IVD (4V03=>A B8:0 in vitro), =01V@, @50:FVO 03;NB8= 0FVW=B8 A8@>20B:0 E. coli I ?>;V20;5=B=0, 1 <; 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4@V646>289 5:AB@0:B- 5,253/;, 3;N:>70- 7,53/;, ;0:B>70- 2,53/;, =0B@VN 0F5B0B- 0,53/;, 0A:>@1V=>20 :8A;>B0-0,53/;, <03=VN E;>@84-0,53/;, F8AB5W=C 3V4@>E;>@84- 0,53/;.7362697 0;>=0B Enterobacteriaceae, 2V420@, :C;LBC@0;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro )0;>=0B 030@, 5003@.1HB30@ <V:@>1V>;>3VG=89- 8,53/;, =0B@VN <0;>=0B- 33/;, 0<>=VN E;>@84- 23/;, 3V4@>D>AD0B :0;VN- 13/;, 4@V646>289 5:AB@0:B-0,53/;, 1@><B8<>;>289 A8=V9-0,033/;.7458546 30@ V7 6>2G-5A:C;V></ 0784>< 4;O Enterococcus spp., 6828;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro )=B5@>:>: 030@, 5003@.4HB5?B>= D5@<5=B0B82=89-183/;, 030@ <V:@>1V>;>3VG=89-103/;, :0;VN 3V4@>D>AD0B-3,53/;, 4@V646>289 5:AB@0:B-53/;, 3;N:>70- 23/;, =0B@VN 0784-0,43/;, B@8D5=V;B5B@07>;V9 E;>@8AB89-0,13/;.7558639 30@ N;;5@0-%8=B>=0 4;O 4>A;V465==O 0=B8<V:@>1=>W GCB;82>ABV, 6828;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro )30@ N;;5@0-%V=B>=0, 5003@.6HB5?B>= D5@<5=B0B82=89- 173/;, 030@ <V:@>1V>;>3VG=89- 153/;, :@>E<0;L- 1,53/;, 4@V646>289 5:AB@0:B- 0,53/;.7662080 30@ 4;O Lactobacillus spp., 6828;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro)30@ !01C@> 7 3;N:>7>N, 5003@.4HB;N:>70- 403/;, 030@ <V:@>1V>;>3VG=89- 103/;, ?5?B>= D5@<5=B0B82=89- 93/;, 4@V646>289 5:AB@0:B- 13/;.7761627 30@ 4;O Enterobacteriaceae, 6828;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro )30@ , 5003@.4HB5?B>= D5@<5=B0B82=89-103/;, ;0:B>70- 10 3/;, 030@ <V:@>1V>;>3VG=89- 103/;, =0B@VN AC;LDVB- 2,653/;, :0;VN 3V4@>D>AD0B- 13/;, DC:A8=- 0,35 3/;.7858649 >682=89 030@, 6828;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro)>682=89 030@, 5003@.4HB5?B>= D5@<5=B0B82=89-103/;, 030@ <V:@>1V>;>3VG=89- 103/;, =0B@VN E;>@84- 53/;, 4@V646>289 5:AB@0:B- 33/;.7958650 >682=89 1C;L9>=, 6828;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro )>682=89 1C;L9>= 5003@.2HB5?B>= D5@<5=B0B82=89-103/;, =0B@VN E;>@84- 4,53/;, 4@V646>289 5:AB@0:B- 0,53/;.8058662 30@ 4;O Salmonella/ Shigella spp., 6828;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro )SS-030@, 500 32HB5?B>= D5@<5=B0B82=89-103/;, ;0:B>70- 7 3/;, 030@ <V:@>1V>;>3VG=89- 123/;, =0B@VN F8B@0B- 53/;, 6>2G- 53/;, =0B@VN AC;LDVB- 4,453/;, 70;V;> ;8<>==>:8A;5- 13/;, 4@V646>289 5:AB@0:B- 0,53/;, =59B@0;L=89 G5@2>=89- 0,033/;, 4V0<0=B>289 75;5=89- 0,000333/;.8157778 @>B5070, @5035=B 4;O V<C=>3VAB>EV<VW IVD (4V03=>AB8:0 in vitro )!5@54>28I5 No9 (28O2;5==O ?V3<5=BC ?V>F80=V=C) 500 34HB30@ <V:@>1V>;>3VG=89- 153/;, ?5?B>= D5@<5=B0B82=89- 103/;, :0;V9 AV@G0=>:8A;89- 103/;, <03=V9 E;>@8AB89- 13/;.8258545 30@ V7 AC;LDVB>< 2VA<CBC 4;O Salmonella spp., 6828;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro )VA<CB-AC;LDVB=89 030@, 5003@.3HB5?B>= D5@<5=B0B82=89- 17 3/;, 030@ <V:@>1V>;>3VG=89- 153/;, 3;N:>70- 53/;, =0B@V9 AV@=8AB>:8A;89- 53/;, =0B@VN 3V4@>D>AD0B-43/;, 2VA<CB F8B@0B- 23/;, 4@V646>289 5:AB@0:B- 13/;, AV;L >@0-13/;, 4V0<0=B>289 75;5=89-0,0253/;.8358661 C;L9>= !01C@> 4;O :C;LB82C20==O 3@81V2, 6828;L=5 A5@54>28I5 IVD (4V03=>AB8:0 in vitro )C;L9>= !01C@> 7 3;N:>7>N, 5003@.2HB;N:>70- 403/;, 030@ <V:@>1V>;>3VG=89- 103/;, ?5?B>= D5@<5=B0B82=89- 93/;, 4@V646>289 5:AB@0:B- 13/;.8458690 "@8FC:@>289 70;>78AB89 030@ 4;O 48D5=FV0FVW Enterobacteriaceae IVD (4V03=>AB8:0 in vitro )Triple Sugar Iron Agar "@L>EFC:@>289 70;V7>2<VICNG89 030@2HB!CE89 ?@5?0@0B C 283;O4V 3><>35==>3> A8?CG>3> ?>@>H:C. @83V=0;L=0 702>4AL:0 C?0:>2:0, ?;0AB8:>289 :>=B59=5@ ?> 500 3, 7 :>=B@>;5< 2V4:@8BBO. 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b&&4&R&Sa t+44 lap<yt;QQ"RRRRV d$Ifgd/V $$Ifa$gd/V $$Ifa$gd("RRRRRRRRTTVVVVVʳn_K7&h/VCJOJPJQJ^JaJnHtH&hCJOJPJQJ^JaJnHtHhIh/VPJ^JnHtH,hD(h/VCJOJPJQJ^JaJnHtH,h(h(CJOJPJQJ^JaJnHtH,h(h/VCJOJPJQJ^JaJnHtH,h(hasCJOJPJQJ^JaJnHtH4h(h/VCJKHOJPJQJ^J_H9aJnHtH4h(hBHCJKHOJPJQJ^J_H9aJnHtHVVVV W>W<0000 $$Ifa$gd/Vkd@$$Iflֈ! b&&4&R&Sa t+44 lap<yt;VVVV W>WlWnWWWWWXXXZZ\ \ \\ҷnnnnnnWH4&h;CJOJPJQJ^JaJnHtHhIh/VPJ^JnHtH,hD(h/VCJOJPJQJ^JaJnHtH,h0h0CJOJPJQJ^JaJnHtH,h0h/VCJOJPJQJ^JaJnHtH4h0h/VCJKHOJPJQJ^J_H9aJnHtH4h0h<CJKHOJPJQJ^J_H9aJnHtH,hs_h/VCJOJPJQJ^JaJnHtH,hth/VCJOJPJQJ^JaJnHtH>WnWWWW \ d$Ifgd/V $$Ifa$gd/V \ \\`\\^`^<0000 $$Ifa$gdm=kd@$$Iflֈ! b&&4&R&Sa t+44 lap<yt;\\\\^\`\\\^^Z^\^^^`^l^^^^_f__`````pYE&hb%CJOJPJQJ^JaJnHtH,h0hm=CJOJPJQJ^JaJnHtH<h0hm=CJKHOJPJQJ^J_H9aJmHnHsHtH4h0hm=CJKHOJPJQJ^J_H9aJnHtH,h`Ghm=CJOJPJQJ^JaJnHtH,h)hm=CJOJPJQJ^JaJnHtH&hm=CJOJPJQJ^JaJnHtH&hCJOJPJQJ^JaJnHtH`^l^^_f__`` d$Ifgdm= $$Ifa$gdm=`aaaa6abaaaaaa2b4bbbbccccccccd.d`dtdvddɵllUɵ,h)hm=CJOJPJQJ^JaJnHtH,h)Khm=CJOJPJQJ^JaJnHtH4h)Khm=CJKHOJPJQJ^J_H9aJnHtH,h)Kh)KCJOJPJQJ^JaJnHtH&hm=CJOJPJQJ^JaJnHtH&hCJOJPJQJ^JaJnHtH&h;CJOJPJQJ^JaJnHtHhIhm=PJ^JnHtH`aa6aba<0$$ $$Ifa$gd)K $$Ifa$gdm=kdA$$Iflֈ! b&&4&R&Sa t+44 lap<yt;baaaaa4bbccc d$Ifgd)K $$Ifa$gdm= $$Ifa$gd @ $$Ifa$gd)K cccd.d<0$$ $$Ifa$gd)K $$Ifa$gdm=kdB$$Iflֈ! b&&4&R&Sa t+44 lap<yt;.d`dvddddee d$Ifgd)K $$Ifa$gdm= $$Ifa$gd @ $$Ifa$gd)Kddddddd(e*eeeeeeeeͶteQ=)&hm=CJOJPJQJ^JaJnHtH&hCJOJPJQJ^JaJnHtH&h;CJOJPJQJ^JaJnHtHhIhm=PJ^JnHtH,h)hm=CJOJPJQJ^JaJnHtH&h)KCJOJPJQJ^JaJnHtH,h)Kh)KCJOJPJQJ^JaJnHtH,h)Khm=CJOJPJQJ^JaJnHtH4h)Khm=CJKHOJPJQJ^J_H9aJnHtH.h @CJKHOJPJQJ^J_H9aJnHtHeee6fFf<0$$ $$Ifa$gd@) $$Ifa$gdm=kdC$$Iflֈ! b&&4&R&Sa t+44 lap<yt;e6fDfFffffff2gggggggghHhJhպ}iU>>>,hM[hM[CJOJPJQJ^JaJnHtH&hCJOJPJQJ^JaJnHtH&h;CJOJPJQJ^JaJnHtHhIhm=PJ^JnHtH,h)hm=CJOJPJQJ^JaJnHtH,h@)hm=CJOJPJQJ^JaJnHtH4h@)hm=CJKHOJPJQJ^J_H9aJnHtH&hm=CJOJPJQJ^JaJnHtH,h@)h@)CJOJPJQJ^JaJnHtHFffff2gg d$Ifgd@) $$Ifa$gdm=ggggh<0$$ $$Ifa$gdM[ $$Ifa$gdm=kdD$$Iflֈ! b&&4&R&Sa t+44 lap<yt;hJhhhhij d$IfgdM[ $$Ifa$gdm= $$Ifa$gd @ $$Ifa$gdM[Jhhhhhhhh`ibiijjjjjjη}iUA&hm=CJOJPJQJ^JaJnHtH&hCJOJPJQJ^JaJnHtH&h;CJOJPJQJ^JaJnHtHhIhm=PJ^JnHtH,h)hm=CJOJPJQJ^JaJnHtH&hM[CJOJPJQJ^JaJnHtH,hM[hM[CJOJPJQJ^JaJnHtH,hM[hm=CJOJPJQJ^JaJnHtH4hM[hm=CJKHOJPJQJ^J_H9aJnHtHjjjXjj<0$$ $$Ifa$gd5 $$Ifa$gdm=kdE$$Iflֈ! b&&4&R&Sa t+44 lap<yt;jXjjjjjjjjkJk\k`kfkk lflhljlllnlplպteQ=&hCJOJPJQJ^JaJnHtH&h;CJOJPJQJ^JaJnHtHhIhm=PJ^JnHtH,h)hm=CJOJPJQJ^JaJnHtH,h5hm=CJOJPJQJ^JaJnHtH.h @CJKHOJPJQJ^J_H9aJnHtH4h5hm=CJKHOJPJQJ^J_H9aJnHtH&hm=CJOJPJQJ^JaJnHtH,h5h5CJOJPJQJ^JaJnHtHjjjj\k`kfkkhl d$Ifgd5 $$Ifa$gdm= $$Ifa$gd @ $$Ifa$gd5hljlplll<0$$ $$Ifa$gd> $$Ifa$gdm=kdF$$Iflֈ! b&&4&R&Sa t+44 lap<yt;plllllm8m:mzm~mmnnnnnnnnnnn2oPoooooպxiU&hCJOJPJQJ^JaJnHtHhIhm=PJ^JnHtH,h)hm=CJOJPJQJ^JaJnHtH&h>CJOJPJQJ^JaJnHtH,h>hm=CJOJPJQJ^JaJnHtH4h>hm=CJKHOJPJQJ^J_H9aJnHtH&hm=CJOJPJQJ^JaJnHtH,h>h>CJOJPJQJ^JaJnHtHlm:mzm~mmn d$Ifgd> $$Ifa$gdm= $$Ifa$gd @ $$Ifa$gd>nnn2oPo<0$$ $$Ifa$gd> $$Ifa$gdm=kdG$$Iflֈ! b&&4&R&Sa t+44 lap<yt;Pooooppp r d$Ifgd> $$Ifa$gdm= $$Ifa$gd @ $$Ifa$gd>oppppppppqqr r"r&r(rͶteQ=&hm=CJOJPJQJ^JaJnHtH&hCJOJPJQJ^JaJnHtHhIhm=PJ^JnHtH,h)hm=CJOJPJQJ^JaJnHtH&h>CJOJPJQJ^JaJnHtH,h>h>CJOJPJQJ^JaJnHtH,h>hm=CJOJPJQJ^JaJnHtH4h>hm=CJKHOJPJQJ^J_H9aJnHtH.h @CJKHOJPJQJ^J_H9aJnHtH r"r(rFrnr<0$$ $$Ifa$gd[q $$Ifa$gdm=kdH$$Iflֈ! b&&4&R&Sa t+44 lap<yt;(rFrnrrrrrrrsssst8t:t>>>>>,hpyhpyCJOJPJQJ^JaJnHtH&hCJOJPJQJ^JaJnHtHhIhm=PJ^JnHtH,h)hm=CJOJPJQJ^JaJnHtH&h[qCJOJPJQJ^JaJnHtH,h[qhm=CJOJPJQJ^JaJnHtH4h[qhm=CJKHOJPJQJ^J_H9aJnHtH&hm=CJOJPJQJ^JaJnHtH,h[qh[qCJOJPJQJ^JaJnHtHnrrrrss:t d$Ifgd[q $$Ifa$gdm= $$Ifa$gd @ $$Ifa$gd[q:t}@}B}D}H}J}}}~ ~"~պqq]F7hIhm=PJ^JnHtH,h)hm=CJOJPJQJ^JaJnHtH&h#CJOJPJQJ^JaJnHtH,h#hm=CJOJPJQJ^JaJnHtH,h#hCJOJPJQJ^JaJnHtH4h#hm=CJKHOJPJQJ^J_H9aJnHtH4h#hCJKHOJPJQJ^J_H9aJnHtH&hm=CJOJPJQJ^JaJnHtH,h#h#CJOJPJQJ^JaJnHtHr|||}@}D}J} ~ d$Ifgd# $$Ifa$gdm= $$Ifa$gd @ $$Ifa$gd# ~"~(~b~~<0$$ $$Ifa$gdd $$Ifa$gdm=kd>M$$Iflֈ! 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30@0=BV9=>3> ;8AB0 2V4 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=> ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8), G8 V=H>3> C?>2=>2065=>3> =0 F5 28@>1=8:>< (7 4>:C<5=B0;L=8< ?V4B25@465==O< B0:>3>), O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 B>20@C, O:89 T ?@54<5B>< 70:C?V2;V FL>3> >3>;>H5==O, C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN B0 ?@>?>78FVTN CG0A=8:0. 0@0=BV9=89 ;8AB ?>28=5= 2:;NG0B8 40BC B0 =><5@ >3>;>H5==O, >?@8;N4=5=>3> =0 251-?>@B0;V #?>2=>2065=>3> >@30=C, 0 B0:>6 =072C ?@54<5BC 70:C?V2;V 73V4=> >3>;>H5==O B0 =072C 0<>2=8:0. /:I> 30@0=BV9=89 ;8AB 2840=89 ?@54AB02=8FB2>< G8 DV;VTN 28@>1=8:0, B> CG0A=8: ?>28=5= 2 A:;04V ?@>?>78FVW =040B8 4>:C<5=B0;L=5 ?V4B25@465==O B0:8E ?>2=>2065=L, =040=8E 28@>1=8:>< B>20@C.10453074 030;L=0 ;0:B0B453V4@>35=070 IVD (4V03=>AB8:0 in vitro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in vitro ), @5035=B105-000848-00 !5G>20 :8A;>B0 (4*40 <; + 2*20 <;)2?0:>2R1:$>AD0B=89 1CD5@ 70 <<>;L/; 5@>:A84070 5000 4/; A:>@10B>:A84070 3000 4/; TOOS 0.72 <<>;L/; R2: $>AD0B=89 1CD5@ 70 <<>;L/; 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+ 114 <;)2?0:>2"R1: CD5@ C40 50 <<>;L/; %>;5AB5@8=5AB5@070 600 4/; %>;5AB5@8=>:AV4070 500 4/; 0B0;070 600 4/; TOOS 2 <<>;L/; R2: CD5@ C40 50 <<>;L/; 4-0<V=>0=B8?V@8= 4 <<>;L/; 5@>:AV4070 4 4/<;"  <5B>N 70?>1V30==O 70:C?V2;V D0;LA8DV:0BV2 B0 >B@8<0==O 30@0=BV9 =0 A2>TG0A=5 ?>AB0G0==O B>20@C C :V;L:>ABV, O:>ABV B0 AB@>:0<8 ?@840B=>ABV, CG0A=8: =040T >@83V=0; 30@0=BV9=>3> ;8AB0 2V4 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=> ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8), G8 V=H>3> C?>2=>2065=>3> =0 F5 28@>1=8:>< (7 4>:C<5=B0;L=8< ?V4B25@465==O< B0:>3>), O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 B>20@C, O:89 T ?@54<5B>< 70:C?V2;V FL>3> >3>;>H5==O, C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN B0 ?@>?>78FVTN CG0A=8:0. 0@0=BV9=89 ;8AB ?>28=5= 2:;NG0B8 40BC B0 =><5@ >3>;>H5==O, >?@8;N4=5=>3> =0 251-?>@B0;V #?>2=>2065=>3> >@30=C, 0 B0:>6 =072C ?@54<5BC 70:C?V2;V 73V4=> >3>;>H5==O B0 =072C 0<>2=8:0. /:I> 30@0=BV9=89 ;8AB 2840=89 ?@54AB02=8FB2>< G8 DV;VTN 28@>1=8:0, B> CG0A=8: ?>28=5= 2 A:;04V ?@>?>78FVW =040B8 4>:C<5=B0;L=5 ?V4B25@465==O B0:8E ?>2=>2065=L, =040=8E 28@>1=8:>< B>20@C.10753030 0<0- 3;CB0<V;B@0=AD5@070 (") IVD (4V03=>AB8:0 in vitro ), @5035=B0<03;CB0<V=B@0=AD5@070 " (435<;+218<;)4?0:>2R1:"@8A-1CD5@ 100 <<>;L/; ;VF8;-3;VF8= 150 <<>;L/; R2: L-y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in vitro ), :0;V1@0B>@105-001127-00 C;LB8:0;V1@0B>@ 1D *3<;10D;0:>=V>DV;V7>20=89 :>=B@>;L=89 <0B5@V0; =0 >A=>2V ;N4AL:>W A8@>20B:8. 8:>@8AB>2CTBLAO C 1V>EV<VG=8E A8AB5<0E Mindray BS 4;O :0;V1@C20==O ?@8 :V;L:VA=><C 287=0G5==V @CB8==8E ?0@0<5B@V2 A8@>20B:8  <5B>N 70?>1V30==O 70:C?V2;V D0;LA8DV:0BV2 B0 >B@8<0==O 30@0=BV9 =0 A2>TG0A=5 ?>AB0G0==O B>20@C C :V;L:>ABV, O:>ABV B0 AB@>:0<8 ?@840B=>ABV, CG0A=8: =040T >@83V=0; 30@0=BV9=>3> ;8AB0 2V4 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=> ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8), G8 V=H>3> C?>2=>2065=>3> =0 F5 28@>1=8:>< (7 4>:C<5=B0;L=8< ?V4B25@465==O< B0:>3>), O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 B>20@C, O:89 T ?@54<5B>< 70:C?V2;V FL>3> >3>;>H5==O, C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN B0 ?@>?>78FVTN CG0A=8:0. 0@0=BV9=89 ;8AB ?>28=5= 2:;NG0B8 40BC B0 =><5@ >3>;>H5==O, >?@8;N4=5=>3> =0 251-?>@B0;V #?>2=>2065=>3> >@30=C, 0 B0:>6 =072C ?@54<5BC 70:C?V2;V 73V4=> >3>;>H5==O B0 =072C 0<>2=8:0. /:I> 30@0=BV9=89 ;8AB 2840=89 ?@54AB02=8FB2>< G8 DV;VTN 28@>1=8:0, B> CG0A=8: ?>28=5= 2 A:;04V ?@>?>78FVW =040B8 4>:C<5=B0;L=5 ?V4B25@465==O B0:8E ?>2=>2065=L, =040=8E 28@>1=8:>< B>20@C.10947869 =>68==V 0=0;VB8 :;V=VG=>W EV<VW IVD (4V03=>AB8:0 in vitro ), :>=B@>;L=89 <0B5@V0;105-009117-00 >=B@>;L ClinChem (@V25=L1) (105<;)2?0:>2V>DV;V7>20=89 :>=B@>;L=89 <0B5@V0; =0 >A=>2V ;N4AL:>W A8@>20B:8  <5B>N 70?>1V30==O 70:C?V2;V D0;LA8DV:0BV2 B0 >B@8<0==O 30@0=BV9 =0 A2>TG0A=5 ?>AB0G0==O B>20@C C :V;L:>ABV, O:>ABV B0 AB@>:0<8 ?@840B=>ABV, CG0A=8: =040T >@83V=0; 30@0=BV9=>3> ;8AB0 2V4 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=> ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8), G8 V=H>3> C?>2=>2065=>3> =0 F5 28@>1=8:>< (7 4>:C<5=B0;L=8< ?V4B25@465==O< B0:>3>), O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 B>20@C, O:89 T ?@54<5B>< 70:C?V2;V FL>3> >3>;>H5==O, C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN B0 ?@>?>78FVTN CG0A=8:0. 0@0=BV9=89 ;8AB ?>28=5= 2:;NG0B8 40BC B0 =><5@ >3>;>H5==O, >?@8;N4=5=>3> =0 251-?>@B0;V #?>2=>2065=>3> >@30=C, 0 B0:>6 =072C ?@54<5BC 70:C?V2;V 73V4=> >3>;>H5==O B0 =072C 0<>2=8:0. /:I> 30@0=BV9=89 ;8AB 2840=89 ?@54AB02=8FB2>< G8 DV;VTN 28@>1=8:0, B> CG0A=8: ?>28=5= 2 A:;04V ?@>?>78FVW =040B8 4>:C<5=B0;L=5 ?V4B25@465==O B0:8E ?>2=>2065=L, =040=8E 28@>1=8:>< B>20@C.11047868 =>68==V 0=0;VB8 :;V=VG=>W EV<VW IVD (4V03=>AB8:0 in vitro ), :0;V1@0B>@105-001128-00 0;V1@0B>@ V?V48 (51 <;)1?0:>20;V1@0B>@ 4;O 287=0G5==O ;V?V4V2 <VAB8BL 0?>;V?>?@>B5W= 1, 0?>;V?>?@>B5W= , E>;5AB5@8= HDL-C, E>;5AB5@8= LDL-C  <5B>N 70?>1V30==O 70:C?V2;V D0;LA8DV:0BV2 B0 >B@8<0==O 30@0=BV9 =0 A2>TG0A=5 ?>AB0G0==O B>20@C C :V;L:>ABV, O:>ABV B0 AB@>:0<8 ?@840B=>ABV, CG0A=8: =040T >@83V=0; 30@0=BV9=>3> ;8AB0 2V4 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=> ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8), G8 V=H>3> C?>2=>2065=>3> =0 F5 28@>1=8:>< (7 4>:C<5=B0;L=8< ?V4B25@465==O< B0:>3>), O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 B>20@C, O:89 T ?@54<5B>< 70:C?V2;V FL>3> >3>;>H5==O, C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN B0 ?@>?>78FVTN CG0A=8:0. 0@0=BV9=89 ;8AB ?>28=5= 2:;NG0B8 40BC B0 =><5@ >3>;>H5==O, >?@8;N4=5=>3> =0 251-?>@B0;V #?>2=>2065=>3> >@30=C, 0 B0:>6 =072C ?@54<5BC 70:C?V2;V 73V4=> >3>;>H5==O B0 =072C 0<>2=8:0. /:I> 30@0=BV9=89 ;8AB 2840=89 ?@54AB02=8FB2>< G8 DV;VTN 28@>1=8:0, B> CG0A=8: ?>28=5= 2 A:;04V ?@>?>78FVW =040B8 4>:C<5=B0;L=5 ?V4B25@465==O B0:8E ?>2=>2065=L, =040=8E 28@>1=8:>< B>20@C.111"53301-;N:>70 IVD (4V03=>AB8:0 in vitro ), =01V@, D5@<5=B=89 A?5:B@>D>B><5B@8G=89 0=0;V7";N:>70 !?- =01V@ @5035=BV2 4;O 287=0G5==O :V;L:>ABV 3;N:>78 2 A8@>20BFV/?;07<V :@>2V, 500 287=0G5=L1?0:>2"V?5@3;V:5<VO T ?>:07=8:>< 70E2>@N20==O =0 4V015B. # ?0FVT=BV2 E2>@8E =0 4V015B 28=8:0NBL 45O:V ?@>1;5<8 7 A8=B57>< V=AC;V=C. !:;04 =01>@C 1. 5035=B 1. CD5@: B@8A @ 7.4 - 92 mmol/l (<<>;L/;); D5=>;  0.3 mmol/l (<<>;L/;); 3;N:>7>>:A84070 - 1500 U/l (4/;); ?5@>:A84070 - 1000 U/l (4/;); 4-0<V=>D5=07>=  2.6 mmol/l (<<>;L/;). 2. !B0=40@B. >4=89 @>7G8= 3;N:>78  10.0 mmol/l (<<>;L/;). 3. =B8:>03C;O=B. >=F5=B@0B 25E: =0B@V9 E;>@8AB89 - 4.2 g (3), =0B@V9 DB>@8AB89  0.11 g (3), "  0.2 g (3). 4. =AB@C:FVO 7 28:>@8AB0==O. 5. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 1 - 30 mmol/l (<<>;L/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 5%. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:1 (2 420 @078) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 2. 2. 'CB;82VABL =5 <5=H 1 mmol/l (<<>;L/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 5%. ><?;5:B 1: 1 E 500 ml (<;) !B0=40@B: 1 E 6 ml (<;) =B8:>03C;O=B: 1 E 20 ml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in vitro ), =01V@, D5@<5=B=89 A?5:B@>D>B><5B@8G=89 0=0;V7";0=V=0<V=>B@0=AD5@070-:V=.!? ("-:V=.!?)4?0:>2"87=0G5==O 0:B82=>ABV " 22060TBLAO 1V;LH A?5F8DVG=8< 4;O 4V03=>AB8:8 E2>@>1 ?5GV=:8. 87=0G5==O " 2 ?>T4=0==V 7 287=0G5==O< A!" 28:>@8AB>2CNBL 4;O 4V03=>AB8:8 V=D0@:BC <V>:0@40. !:;04 =01>@C 1. 5035=B 1. CD5@: B@8A @ 7.8 - 100 mmol/l (<<>;L/;),  - 1200 U/l (4/;), L-0;0=V=  500 mmol/l (<<>;L/;). 2. 5035=B 2. !C1AB@0B: NADH  0.18 mmol/l (<<>;L/;), -:5B>3;CB>@0B - 15 mmol/l (<<>;L/;). 3. =AB@C:FVO 7 28:>@8AB0==O. 4. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 4 - 260 U/l (4/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 7 %. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:9 (2 45AOBL @07V2) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 10. 2. 'CB;82VABL =5 <5=H 4 U/l (4/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 7%. ><?;5:B0FVO: 1: 1 D;. E 400 ml (<;) 2: 1 D;. E 100 ml (<;) @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V2 113"52954-030;L=0 0A?0@B0B0<V=>B@0=AD5@07 0 (AST) IVD (4V03=>AB8:0 in vitro ), =01V@, D5@<5=B=89 A?5:B@>D>B><5B@8G=89 0=0;V7"A?0@B0B0<V=>B@0=AD5@070-:V=.!? (!"-:V= !?) 4?0:>2"V428I5=89 @V25=L !" 2 A8@>20BFV :@>2V =5 T A?5F8DVG=8< ?>:07=8:>< 70E2>@N20==O ?5GV=:8. 8:>@8AB>2CTBLAO, 3>;>2=8< G8=><, 4;O 4V03=>AB8:8 B0 :>=B@>;N ?5@51V3C E2>@>1 ?5GV=:8 ?>@O4 7 V=H8<8 D5@<5=B0<8, B0:8<8 O: A" V ;C6=0 D>AD0B070. "0:>6 287=0G5==O !" 28:>@8AB>2CTBLAO 4;O :>=B@>;N AB0=C ?0FVT=BV2 ?VA;O V=D0@:BC <V>:0@40, ?@8 E2>@>1V A:5;5B=8E <'O7V2 B0 V=. !:;04 =01>@C 1. 5035=B 1. CD5@: B@8A @ 7.8 - 80 mmol/l (<<>;L/;);  - 800 U/l (4/;);  - 600 U/l (4/;); L-0A?0@B0B - 200 mmol/l (<<>;L/;). 2. 5035=B 2. !C1AB@0B: NADH  0.18 mmol/l (<<>;L/;); a-:5B>3;CB>@0B - 15 mmol/l (<<>;L/;). 3. =AB@C:FVO 7 28:>@8AB0==O. 4. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 4 - 260 U/l (4/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 7 %. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:9 NaCl (2 45AOBL @07V2) 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 10. 2. 'CB;82VABL =5 <5=H 4 U/l (4/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 7%. @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V2114"52928-030;L=0 ;C6=0 D>AD0B070 (ALP) IVD (4V03=>AB8:0 in vitro ), =01V@, D5@<5=B=89 A?5:B@>D>B><5B@8G=89 0=0;V7"C6=0 D>AD0B070-:V=.!? ($-:V=.!?)2?0:>2"1V;LH5==O 0:B82=VABV $ 3>;>2=8< G8=>< 7CAB@VG0TBLAO ?@8 70E2>@N20==OE :VAB>: (E2>@>1V 5465B0, >AB5><0;OFVV, @0EVBV) 01> 70E2>@N20==OE ?5GV=:8 (E>;5AB07, >1AB@C:B82=5 70E2>@N20==O ?5GV=:8, 35?0B8B, A0@:>W4>7, 35?0B>B>:A8G=V 28?04:8,<5E0=VG=V9 6>2BV;L=8FV), <5B0AB07C20==O 2 :VAB:8 B0 ?5GV=:C. !:;04 =01>@C 1. 5035=B 1. CD5@: 4V5B0=>;0<V= @ 10.4 - 1 mmol/l (<<>;L/;); <03=VN E;>@84 - 0.5 mmol/l (<<>;L/;). 2. 5035=B 2. !C1AB@0B: ?-=VB@>D5=V;D>AD0B - 10 mmol/l (<<>;L/;). 3. =AB@C:FVO 7 28:>@8AB0==O. 4. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 20 - 1200 U/l (4/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 5 %. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:9 (2 10 @07V2) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 10. 2. 'CB;82VABL =5 <5=H 20 U/l (4/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 5%. @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V211552941 - 030;L=0 0<V;070 IVD (4V03=>AB8:0 in vitro ), @5035=B;LD0-<V;070-:V=.!?1?0:>2"87=0G5==O ?@>2>48BLAO 4;O 4V03=>AB8:8 B0 :>=B@>;N 70E2>@N20=L ?V4H;C=:>2>W 70;>78, O: 3>AB@>3> B0: V E@>=VG=>3> ?0=:@50B8BC. :B82=VABL -0<V;078 B0:>6 <>65 E0@0:B5@87C20B8 6>2G=V 01> H;C=:>2>-:8H:>2V 70E2>@N20==O B0 V=HV ?>@CH5==O. !:;04 =01>@C 1. 5035=B 1. CNPG3 - 2.25 mmol/l (<<>;L/;), MES @ 6.2, =0B@VN E;>@84 -350 mmol/l (<<>;L/;), :0;LFVN 0F5B0B - 6 mmol/l (<<>;L/;), :0;VN BV>FV>=0B - 900 mmol/l (<<>;L/;), =0B@VN 07V4 - 0.95 g/l (3/;). 2. =AB@C:FVO 7 28:>@8AB0==O. 3. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 20 - 2000 U/l (4/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 5 %. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:1 (2 420 @078) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 2. 2. 'CB;82VABL =5 <5=H 20 U/l (4/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 5 %. @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V211653587- !5G>28=0 (Urea) IVD (4V03=>AB8:0 in vitro ), =01V@, D5@<5=B=89 A?5:B@>D>B><5B@8G=89 0=0;V7!5G>28=0 !?4?0:>2"V428I5=89 @V25=L A5G>28=8 2 :@>2V A?>AB5@V30TBLAO ?@8 70E2>@N20==V =8@>:, 7;>O:VA=8E ?CE;8=0E A5G>282V4=8E H;OEV2 B0 ?5@54<VEC@>2>W 70;>78, E2>@>1V 44VA>=0, ?>A8;5=><C @>7?04C 1V;:V2, H>FV, 7=52>4=5==V, 4VTB0E 7 =04;8H:>28< @V2=5< 1V;:V2. =865==O A5G>28=8 2 :@>2V 1C20T DV7V>;>3VG=8< ?@8 203VB=>ABV. !:;04 =01>@C 1. 5035=B 1. CD5@: D>AD0B - 50 mmol/l (<<>;L/;); -" - 2 mmol/l (<<>;L/;); =0B@VN A0;VF8;0B - 400 mmol/l (<<>;L/;); =0B@VN =VB@>?@CA84 - 10 mmol/l (<<>;L/;). 2. 5035=B 2. CD5@: 0B@VN 3V?>E;>@8B - 140 mmol/l (<<>;L/;); =0B@VN 3V4@>:A84 - 150 mmol/l (<<>;L/;). 3. 5035=B 3. =78<8: C@5070 - 3000 4/ml (<;). 4. !B0=40@B. >4=89 @>7G8= A5G>28=8 - 8.3 mmol/l (<<>;L/;). 5. =AB@C:FVO 7 28:>@8AB0==O 6. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 2-33.3 mmol/l (<<>;L/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 5%. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:1 (2 420 @078) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 420. 2. 'CB;82VABL =5 <5=H 2 mmol/l (<<>;L/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 5%. @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V2117"53251-@50B8=V= IVD (4V03=>AB8:0 in vitro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mmol/l (<<>;L/;). 2. 5035=B 2. C6=89 @5035=B: =0B@VN 3V4@>:A84 - 1.15 mol/l (<>;L/;). 3. 5035=B 3. A046C20G: B@8E;>@>F5B>20 :8A;>B0  1.22 mol/l (<>;L/;). 4. !B0=40@B. >4=89 @>7G8= :@50B8=V=C, 166 mol/l (<:<>;L/;). 5. =AB@C:FVO 7 28:>@8AB0==O. 6. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1.V=V9=VABL28<V@N20;L=>3> 4V0?07>=C: 30 - 885 mol/l (<:<>;L/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 5%. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:1 (2 420 @078) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 2. 2. 'CB;82VABL =5 <5=H 30 mol/l (<:<>;L/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 5%. @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V2118"53001-030;L=0 :@50B8=:V=070 IVD (4V03=>AB8:0 in vitro ), =01V@, D5@<5=B=89 A?5:B@>D>B><5B@8G=89 0=0;V7"@50B8=:V=070-:V=.!?2?0:>2"V428I5=V 7=0G5==O K A?>AB5@V30NBLAO ?@8 70E2>@N20==OE <'O7>2>3> A:5;5BC V ?VA;O V=D0@:BC <V>:0@40 !:;04 =01>@C 1. 5035=B 1. CD5@: <V407>; @ 6.7 - 125 mmol/l (<<>;L/;); D-3;N:>70 - 25 mmol/l (<<>;L/;); N-0F5B8;-L-F8AB58= (N!) - 25 mmol/l (<<>;L/;); 0F5B0B <03=57VV  1.25 mmol/l (<<>;L/;); $  2.52 mmol/l (<<>;L/;); "  2.02 mmol/l (<<>;L/;); 35:A>:V=070 e" 6 800 U/l (4/;). 2. 5035=B 2. =78<8: $  15.2 mmol/l (<<>;L/;); $ - 25 mmol/l (<<>;L/;); 4V045=>78=-5-?5=B0D>AD0B - 103 mmol/l (<<>;L/;), 6$- e"8 800 U/l (4/;); :@50B8=D>AD0B - 250 mmol/l (<<>;L/;). 3. =AB@C:FVO 7 28:>@8AB0==O. 4. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 20 - 1000 U/l (4/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 7 %. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:9 (2 45AOBL @07V2) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 10. 2. 'CB;82VABL =5 <5=H 20 U/l (4/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 7%. @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V211953460-"@83;VF5@848 IVD (4V03=>AB8:0 in vitro ), =01V@, D5@<5=B=89 A?5:B@>D>B><5B@8G=89 0=0;V7"@83;VF5@848 !?3 ?0:>2"@8 V=:C10FVW 7@07:0 B@83;VF5@84V2 7 ;V?>?@>B5W=;V?07>N () 2V41C20TBLAO @50:FVO 7 CB2>@5==O< 2V;L=>3> 3;VF5@8=C B0 2V;L=8E 68@=8E :8A;>B. ;VF5@8= B0 "$, 2 ?@8ACB=>ABV 3;VF5@>;:V=078 ?@>E>4OBL @O4 D5@<5=B0B82=8E @50:FV9 7 CB2>@5==O< 7010@2;5=>3> ?@>4C:BC (G5@2>=>3> :>;L>@C): =B5=A82=VABL 7010@2;5==O ?@O<> ?@>?>@FV9=0 :>=F5=B@0FVW B@83;VF5@84V2 2 ?@>1V. !:;04 =01>@C 1. 5035=B 1. GOOD @ 6.3 -50 mmol/l (<<>;L/;); @-E;>@>D5=>; -2 mmol/l (<<>;L/;);  -150000 U/l (4/;); 3;VF5@>;:V=070 - 500 U/l (4/;); 3;VF5@>;-3->:A84070 - 3500 U/l (4/;); 4-$ - 0.1 mmol/l (<<>;L/;); "$ - 0.1 mmol/l (<<>;L/;). 2. !B0=40@B. >7G8= B@83;VF5@84V2  2.25 mmol/l (<<>;L/;). 3. =AB@C:FVO 7 28:>@8AB0==O. 4. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 0.11 - 11 mmol/l (<<>;L/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 5%. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:1 (2 420 @078) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 420. 2. 'CB;82VABL =5 <5=H 0.11 mmol/l (<<>;L/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 5%. @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V2120"53359-030;L=89 E>;5AB5@8= IVD (4V03=>AB8:0 in vitro ), =01V@, D5@<5=B=89 A?5:B@>D>B><5B@8G=89 0=0;V7"%>;5AB5@8= !?1?0:>2"030;L=89 E>;5AB5@8= :@>2V, CB2>@NT :>;L>@>289 :><?;5:A, 0 @O4V A:;04=8E D5@<5=B0B82=8E @50:FV9. =B5=A82=VABL 7010@2;5==O ?@O<> ?@>?>@FV9=0 :>=F5=B@0FVW E>;5AB5@8=C C 7@07:C. !:;04 =01>@C 1. 5035=B 1. PIPES @ 6.9 - 90 mmol/l (<<>;L/;); D5=>; - 26 mmol/l (<<>;L/;); % - 1000 U/l (4/;); % - 300 U/l (4/;), ?5@>:A84070 - 650 U/l (4/;); 4-0<V=>D5=07>=  0.4 mmol/l (<<>;L/;). 2. !B0=40@B. >7G8= E>;5AB5@8=C - 5.16 mmol/l (<<>;L/;). 3. =AB@C:FVO 7 28:>@8AB0==O. 4. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 0.25 - 20 mmol/l (<<>;L/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 5%. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:1 (2 420 @078) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 420. 2. 'CB;82VABL =5 <5=H 0.25 mmol/l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mmol/l (<<>;L/;); A>;O=0 :8A;>B0 - 50 mmol/l (<<>;L/;); ! - 7 mol/l (<>;L/;). 2. 5035=B 2. VB@8B =0B@VN - 29 mmol/l (<<>;L/;). 3. =AB@C:FVO 7 28:>@8AB0==O. 4. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 1.71 - 300 mol/l (<:<>;L/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 7%. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:1 (2 420 @078) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 420. 2. 'CB;82VABL =5 <5=H 1.71 mol/l (<:<>;L/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 7%. @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V2.122"53233 ->='N3>20=89 (?@O<89, 72'O70=89) 1V;V@C1V= IVD (4V03=>AB8:0 in vitro ), =01V@,A?5:B@>D>B><5B@8G=89 0=0;V7"V;V@C1V= ?@O<89 !?4?0:>2"030;L=89 1V;V@C1V= (?@O<89 B0 =5?@O<89) ?5@5B2>@NTBLAO C :>;L>@>289 :><?;5:A 07>1V;V@C1V=C ?V4 2?;82>< 4V07>B>20=>W AC;LD0=V;>2>W :8A;>B8 C :8A;><C A5@54>28IV.  42>E D@0:FV9 1V;V@C1V=C 157?>A5@54=L> C 2>4=><C @>7G8=V ?@89<0T CG0ABL BV;L:8 ?@O<89 1V;V@C1V=.  B>9 G0A O: =5?@O<89 1V;V@C1V= ?>B@V1=> @>7G8=8B8 7 48<5B8;AC;LD>:A84>< (!). =B5=A82=VABL :>;L>@C ?@>?>@FV9=0 :>=F5=B@0FVW 1V;V@C1V=C C 7@07:C. !:;04 =01>@C 1. 5035=B 1. !C;LD0=V;>20 :8A;>B0 - 30 mmol/l (<<>;L/;); A>;O=0 :8A;>B0 - 150 mmol/l (<<>;L/;). 2. 5035=B 2. VB@8B =0B@VN - 29 mmol/l (<<>;L/;). 3. =AB@C:FVO 7 28:>@8AB0==O. 4. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 1.71 - 300 mol/l (<:<>;L/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 7%. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:1 (2 420 @078) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 420. 2. 'CB;82VABL =5 <5=H 1.71 mol/l (<:<>;L/;). 3. >5DVFVT=B 20@V0FVW @57C;LB0BV2 287=0G5=L  =5 1V;LH 7%. @83V=0; 30@0=BV9=>3> ;8AB0 28@>1=8:0 (?@54AB02=8FB20, DV;VW 28@>1=8:0, O:I> WE 2V4?>2V4=V ?>2=>2065==O ?>H8@NNBLAO =0 B5@8B>@VN #:@0W=8) 01> ?@54AB02=8:0, 48;5@0, 48AB@81'NB>@0, C?>2=>2065=>3> =0 F5 28@>1=8:><, O:8< ?V4B25@46CTBLAO <>6;82VABL ?>AB02:8 70?@>?>=>20=>3> B>20@C, O:89 T ?@54<5B>< 70:C?V2;V F8E B>@3V2 C :V;L:>ABV, 7V AB@>:0<8 ?@840B=>ABV B0 2 B5@<V=8, 287=0G5=V FVTN 4>:C<5=B0FVTN :>=:C@A=8E B>@3V2 B0 ?@>?>78FVTN :>=:C@A=8E B>@3V2 CG0A=8:0 B>@3V2.123"53072-030;L=0 ;0:B0B453V4@>35=070 IVD (4V03=>AB8:0 in vitro ), =01V@, D5@<5=B=89 A?5:B@>D>B><5B@8G=89 0=0;V7"0:B0B453V4@>35=070-:V=.!? (-:V=.!?)1?0:>2"V428I5=89 @V25=L D5@<5=BC 2V47=0G0TBLAO 2 A8@>20BFV :@>2V ?@8 V=D0@:BV <V>:0@40, E2>@>10E ?5GV=:8, ;59:>70E, 70E2>@N20==OE =8@>:, <'O7>2V9 48AB@>DVW V 0=5<VW, ?CE;8=0E, ?0=:@50B8BV. !:;04 =01>@C 1. 5035=B 1. CD5@: V<V407>; - 65 mmol/l (<<>;L/;); ?V@C20B - 0.6 mmol/l (<<>;L/;). 2. 5035=B 2. !C1AB@0B: NADH - 0.18 mmol/l (<<>;L/;). 3. =AB@C:FVO 7 28:>@8AB0==O. 4. 0A?>@B 01> A5@B8DV:0B. =0;VB8G=V E0@0:B5@8AB8:8 1. V=V9=VABL 28<V@N20;L=>3> 4V0?07>=C: 30 - 1300 U/l (4/;). V4E8;5==O 2V4 ;V=V9=>ABV =5 ?5@528ICT 5 %. /:I> >B@8<0=V @57C;LB0B8 1C;8 1V;LH5, =V6 <56V ;V=V9=>ABV, @>7254VBL 7@07:8 1:9 (2 45AOBL @07V2) NaCl 9 g/l (3/;) B0 ?><=>6B5 @57C;LB0B =0 10. 2. 'CB;82VABL =5 <5=H 30 U/l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jlnpr~ jlpr~:tɵ}mYYYYYYYYY'hL4hL4CJOJPJQJ\^JaJheCJOJPJQJ^JaJ!heCJOJPJQJ\^JaJ'h61heCJOJPJQJ\^JaJ$h61heCJOJPJQJ^JaJ&heCJOJPJQJ^JaJnHtH&hCJOJPJQJ^JaJnHtH&h;CJOJPJQJ^JaJnHtHhIhePJ^JnHtH"jlr~<0$$7$8$H$Ifa$gde $$Ifa$gdekdX$$Iflֈ! 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